Dietary Cholesterol Associated with Increased Cancer Risk

A study published in Annals of Oncology found that dietary cholesterol (found only in animal-based foods, like meat and dairy products) was associated with an increased risk of cancer.

Researchers at the Centre for Chronic Disease Prevention and Control, Public Health Agency of Canada mailed questionnaires to thousands of men and women with various types of cancers and controls without cancer, asking about their eating habits two years prior to the study to evaluate the amount of cholesterol they consumed.

The researchers found that cholesterol intake was associated with elevated risk of breast cancer(specifically postmenopausal women), and cancers of the stomach, colon, rectum, pancreas, lung, breast cancer , testis, kidney, bladder and non-Hodgkin lymphoma. People who had the highest intake of cholesterol were 40 to 70 percent more likely to develop these cancers as compared to people with the lowest consumption of cholesterol.

The authors write, “Our findings add to the evidence that high cholesterol intake is linked to increased risk of various cancers. A diet low in cholesterol may play a role in the prevention of several cancers.”

Weill Cornell’s Dr. Andrew Dannenberg Receives Breast Cancer Research Foundation Grant

The Breast Cancer Research Foundation (BCRF) has awarded a grant to Dr. Andrew Dannenberg of Weill Cornell Medical College to fund research into the link between obesity, inflammation and breast cancer. Dr. Dannenberg is the director of the Cancer Center at NewYork-Presbyterian Hospital/Weill Cornell Medical Center. The grant is funded through Bloomingdale’s annual Pink Campaign.

“If left unchecked over long periods of time, inflammation can predispose people to a variety of illnesses, including breast cancer,” said Dr. Dannenberg. “Understanding specific ways inflammation works on a molecular level will help us develop better and safer ways to prevent and treat the disease.”

In the past year, Dr. Dannenberg and colleagues discovered links between obesity, breast inflammation and molecular changes known to effect the formation and progression of breast cancer. Inflammation was previously known to predispose people to other tumor types, but this research was the first evidence for breast tumors. These findings provide an opportunity for developing breast cancer risk reduction strategies.